Is ‘Ozempic Penis’ Real? Experts Weigh In on GLP-1 Weight Loss Drug Side Effect

A wave of Reddit users have reported what they’re calling the “Ozempic penis” — a surprising observation that their penis appears larger after taking GLP-1 medications like Ozempic, Wegovy, or Mounjaro. But is this a real side effect or simply a visual illusion?

What Is the ‘Ozempic Penis’ Phenomenon?

On Reddit forums such as r/Ozempic, users are sharing claims of penile growth of up to 1.5 inches. One user even stated, “I gained about 1 inch,” while others chimed in with similar experiences after losing significant weight while on these medications.

However, medical professionals clarify that this change is likely not actual growth, but rather the appearance of increased size due to fat loss around the pubic area.

What Do Medical Experts Say?

Dr. Pamela Tambini, a board-certified physician, explained that GLP-1 drugs do not directly cause penis growth. “There’s no known biological mechanism that links these medications to the enlargement of genital tissue,” she said.

Instead, weight loss in the lower abdomen may expose more of the base of the penis that was previously hidden by fat, creating the illusion of increased length.

Dr. Stanton Honig from Yale School of Medicine agreed, referring to this condition as “hidden penis” — a common occurrence in overweight individuals that can resolve with weight loss or surgery.

Other Contributing Factors

While fat reduction is the most probable explanation, experts also point to other factors:

• Improved blood flow from enhanced metabolic health may enhance erectile quality.
• Boosted self-confidence and body image may affect perception.
• Better testosterone levels and hormonal balance after weight loss may play a role.

Is There Any Risk?

In most cases, a perceived increase in penis size isn’t medically concerning. However, Dr. Tambini advises discussing any unexpected changes — positive or negative — with a doctor, especially if there are issues with erectile function, sensitivity, or libido.

It’s also worth noting that many men using Ozempic or similar drugs may have diabetes or cardiovascular risk factors, both of which are associated with erectile dysfunction (ED).

How to Accurately Measure Penis Size

For those curious about their own changes, experts recommend using consistent methods:

• Measure from the pubic bone to the tip of the penis while erect.
• Perform measurements under the same conditions (e.g., room temperature, arousal level).
• Record girth at the midpoint of the shaft.

Keep in mind that perception alone can be influenced by psychological well-being, not just physical change.

Bottom Line

There is no clinical evidence that GLP-1 drugs like Ozempic cause real penis enlargement. However, fat loss around the pubic area may lead to more of the penis becoming visible, and improved blood flow may enhance erectile quality — creating a noticeable difference for some men.

As with any medication, it’s important to talk to your healthcare provider about side effects, expectations, and body changes you may experience.

For more updates on metabolic health and men’s wellness, visit SasabhsuHealth.com.