New Clinical Trial Reveals Promising Results
A new study presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting shows that following an anti-inflammatory diet may significantly improve survival outcomes for people with stage 3 colon cancer.
Researchers found that colon cancer patients who adhered to anti-inflammatory eating habits had longer overall survival rates compared to those consuming pro-inflammatory foods.
How Inflammation Affects Colon Cancer
Inflammation plays a key role in cancer development and progression. A diet high in inflammatory foods — such as red and processed meats, sugary beverages, and refined grains — is linked to a higher cancer risk. In contrast, anti-inflammatory foods may help suppress tumor growth and support immune function.
“Inflammation damages the body and increases the risk for tumor formation,” explained Dr. Nilesh Vora, a board-certified oncologist. “The more we reduce systemic inflammation, the better our chances of improving survival.”
Study Findings: Diet & Lifestyle Combined
- Participants: 1,625 patients with stage 3 colon cancer
- Those on a pro-inflammatory diet had an 87% higher risk of death.
- Participants who combined an anti-inflammatory diet with moderate physical activity had a 63% lower risk of death.
Physical activity included walking at a 2–3 mph pace for at least an hour, three times per week.
Why Anti-Inflammatory Foods Help
According to Dr. Dana Hunnes, senior dietitian at UCLA Medical Center, anti-inflammatory diets are rich in phytonutrients, fiber, and healthy fats — all of which contribute to a healthier gut microbiome and may help reduce tumor-promoting inflammation.
She also emphasized the importance of short-chain fatty acids produced when gut bacteria digest fiber. These acids help protect the colon and may inhibit cancer growth.
Top Anti-Inflammatory Foods for Colon Health
Incorporate these foods into your daily meals:
- Leafy greens: Spinach, kale, collard greens
- Berries: Blueberries, strawberries, raspberries
- Nuts & seeds: Almonds, flaxseeds, chia seeds
- Legumes: Lentils, chickpeas, black beans
- Whole grains: Quinoa, brown rice, oats
- Beverages: Green tea, black tea, and coffee in moderation
These foods are packed with antioxidants, vitamins, and compounds that may reduce inflammation and support colon health.
Takeaway: Diet and Exercise Matter
This research underscores the growing evidence that diet and lifestyle changes can influence cancer survival rates. While more research is needed to understand the biological mechanisms, eating anti-inflammatory foods and staying active appear to offer tangible benefits.
If you’re a colon cancer survivor or at risk, talk to your doctor or a registered dietitian about incorporating anti-inflammatory foods and physical activity into your routine.